GENXMAP offers a comprehensive range of gene expression analysis services for the study of biomarkers of interest or gene panels. Our expertise enables you to gain a detailed understanding of which genes are activated or repressed under various conditions, providing crucial insights into disease mechanisms, treatment responses, and complex biological processes. With advanced technologies such as RT-qPCR and digital PCR, along with rigorously optimized protocols, we ensure precise and reliable data, essential for making informed decisions and advancing your research projects.
Optimal Precision in Gene Expression
Custom Gene Expression Analysis
We offer customized gene expression analysis services tailored to your specific needs.
RNA Extraction and Purification
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Specialized in high-quality RNA extraction from various samples, including tissues, cells, blood, and complex matrices like FFPE tissues. Our customized protocols ensure RNA integrity, with advanced quality control (Qubit, Nanodrop, Fragment Analyzer) to deliver reliable results, even for large-scale projects.
Gene Expression Profiling
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RT-qPCR allows for relative quantification of gene expression with high sensitivity and specificity. It is ideal for validating RNA-Seq genes and is commonly used in clinical research, diagnostics, and monitoring gene expression.
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Digital PCR (dPCR) provides absolute quantification and ultra-sensitive detection. This technology is ideal for analyzing rare and lowly expressed transcripts (e.g., circulating tumor DNA).
TaqMan Gene Expression Assays
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TaqMan assays provide high specificity and sensitivity for accurate gene expression quantification. With their customization and multiplexing capabilities, they enable targeted and simultaneous analysis of multiple genes. Used in clinical research, biomarker validation, and the analysis of low-expression genes, they ensure reliable results with minimal background noise.
GENXMAP, your trusted partner to support you in your research.
Optimized and Transparent Services
Our Go/No-Go processes allow you to track the progress of your project in real-time. At each stage, you validate the transition to the next, ensuring complete control and maximum transparency throughout the entire process.
Our optimized timelines ensure fast and efficient execution of each project while meeting your specific requirements. This system ensures proactive time management, minimizing delays and maximizing productivity to deliver results that align with your expectations.
Our tailored processes are designed to meet the unique needs of each project, offering flexibility and personalized follow-up. This system ensures rigorous control while delivering accurate results that align with your expectations.
Our detailed analyses guarantee reliable and in-depth results tailored to each study. With cutting-edge tools and proven methodologies, we provide a precise understanding of genetic data, while adhering to the highest standards of quality and scientific rigor.
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Precision, Innovation, and Reliability at the Service of Your Discoveries.
Explore our blog to learn how our cutting-edge technologies and advanced analyses are opening new perspectives in scientific research and clinical applications.
Service Details
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Nous définissons clairement vos objectifs scientifiques pour guider votre étude, qu’il s’agisse d’analyser des marqueurs spécifiques via RT-qPCR ou d’explorer plus en profondeur avec des analyses comme le Bulk RNA-seq ou le single-cell RNA-seq. Chaque approche est adaptée à vos besoins pour maximiser la pertinence et la précision des résultats.
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Vous nous précisez les types d’échantillons que vous souhaitez analyser (tissus, cellules, échantillons environnementaux...), ce qui nous permet d’adapter le processus d’extraction pour garantir la qualité et la précision des résultats.
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Sélection de la méthodologie : En fonction de vos objectifs, nous vous conseillons sur la méthode la plus appropriée pour l'extraction et le choix d'une approche exploratoire ou ciblée.
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Planification du projet et personnalisation :
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Ciblage spécifique ou séquençage global : Si nécessaire, nous élaborons un panel spécifique pour cibler des gènes ou groupes d'intérêt particuliers, ou optons pour une approche globale pour analyser la diversité génétique dans son ensemble.
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Estimation du budget et du calendrier
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Validation du budget : Nous vous fournissons une estimation claire du coût du projet en fonction de la méthodologie choisie, du nombre d’échantillons, de la technique d'analyse choisie
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Planification temporelle : Une estimation du délai pour la préparation des échantillons, et les analyses transcriptomiques (exploratoire ou ciblée) est partagée, avec des points de contrôle réguliers pour suivre l’avancement.
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Suivi et soutien continu
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Accompagnement dans le suivi : Une fois le projet lancé, nous vous accompagnons tout au long du processus, de la récolte des données brutes au soutien bioinformatique pour interpréter les résultats, avec des rapports personnalisés et des recommandations pour les prochaines étapes.
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We clearly define your scientific objectives to guide your study, whether it's analyzing specific markers via RT-qPCR or exploring in more depth with analyses like Bulk RNA-seq or single-cell RNA-seq. Each approach is tailored to your needs to maximize the relevance and precision of the results.
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You specify the types of samples you wish to analyze (tissues, cells, environmental samples...), allowing us to adapt the extraction process to ensure quality and accuracy.
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Methodology Selection:
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Based on your objectives, we advise on the most suitable method for extraction and whether to choose an exploratory or targeted approach.
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Project Planning and Customization:
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Specific Targeting or Global Sequencing: If necessary, we design a specific panel to target genes or groups of interest, or opt for a global approach to analyze genetic diversity as a whole.
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Budget and Timeline Estimation:
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Budget Validation: We provide a clear cost estimate based on the chosen methodology, number of samples, and selected analysis technique.
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Timeline Planning: We share an estimated timeline for sample preparation and transcriptomic analysis (exploratory or targeted), with regular checkpoints to monitor progress.
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Ongoing Support and Follow-up:
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Support Throughout the Process: Once the project is launched, we support you throughout the process, from raw data collection to bioinformatics assistance for result interpretation, with personalized reports and recommendations for next steps.
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Step 0 >> Sample Reception Control
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Visual evaluation for quantity and quality.
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Report and client decision "Go / No-Go" for the next steps in the process.
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Step 1 >> Sample Preparation and RNA Extraction
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RNA Extraction: Optimized protocols to ensure high-quality extraction, even from difficult sample types (FFPE tissues, rare cells, etc.) using the following methods: Trizol, columns, or magnetic beads.
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Quantification and Quality Assessment: Verification of RNA quantity and quality using spectrophotometers (Nanodrop), Qubit, or Fragment Analyzer (Qiaxcel).
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Step 2 >> Reverse Transcription (RT)
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We offer different enzymes tailored to your needs (normal RNA amount, low-input RNA).
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Step 3 >> qPCR
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SYBR Green techniques
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TaqMan
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Digital PCR (ddPCR) > New in 2025.
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Step 4 >> Data Analysis
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We offer different levels of analysis:
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Relative expression analysis
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Fold change analysis (comparing relative expression based on conditions)
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Biostatistical analyses (statistical analysis and graph formatting).
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Step 5 >> Result Delivery
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Result Formats: Raw files (Excel) provided.
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Detailed Report: Includes a summary of results, visualizations (graphs), biological interpretation, and recommendations for next steps.
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Delivery Methods: Available through a secure online platform, sent via email, or a presentation meeting for result discussion.
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Follow-up and Support: Post-delivery assistance for clarifications, revisions, or additional analyses.
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Delivery Timeline: Generally between 1 to 2 weeks, depending on project complexity.
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