Uncover Cellular Heterogeneity with Single-Cell RNA-Seq

 

Our Single-Cell RNA Sequencing (scRNA-Seq) service at GENXMAP allows you to explore the transcriptomic landscape at an unprecedented resolution—down to the level of individual cells. This cutting-edge technology is essential for understanding complex tissues, cellular diversity, and dynamic biological processes such as development, differentiation, and disease progression.

 

• Advantages of Single-Cell RNA-Seq:
   

  • Single-Cell Resolution: Analyze gene expression in individual cells, uncovering cellular heterogeneity that would be obscured in bulk RNA-Seq, and revealing the complexity within tissue samples.

  • Advanced Technologies:

    • 10X Genomics: Offers high-throughput, scalable solutions for capturing thousands of cells per sample, providing detailed insights into gene expression across large cell populations. (applied for Mice and Human)

    •  Parse Biosciences: Features a flexible and scalable approach with their Split-Pool Ligation-based Transcriptome sequencing (SPLiT-Seq) technology, enabling large-scale single-cell studies with high resolution (applied for

    • Singleron: Delivers high-quality single-cell data with optimized protocols for diverse sample types, including challenging and complex tissues, ensuring reliable and reproducible results.

    •  PIPseq: Features innovative technology for capturing and sequencing RNA from individual cells from different sample types, known for its ability to generate high-quality data with a focus on transcript stability and integrity.

 

•  Applications of Single-Cell RNA-Seq:
   

  • Cell Type Identification: Distinguish between different cell types and states within a heterogeneous population, critical for studying complex tissues, tumors, and immune responses.

  • Trajectory Analysis: Map cell differentiation pathways and uncover lineage relationships by examining changes in gene expression over time, providing insights into development and disease progression.

  • Novel Cell Discovery: Identify rare or previously unknown cell types that play critical roles in health and disease, advancing the understanding of cellular functions and pathologies.

  • Spatial and Temporal Insights: When combined with spatial transcriptomics, gain an understanding of the spatial organization of cells and their interactions, adding another layer of biological context to your data.

 

By leveraging the latest in single-cell technologies, GENXMAP’s Single-Cell RNA-Seq service is designed to provide you with detailed, high-resolution insights into cellular behavior. Whether you are focused on identifying new therapeutic targets, understanding disease mechanisms, or exploring the cellular basis of health and disease, our service is your gateway to cutting-edge research and discovery.